Research library / Fasting and calorie restriction

2 years of calorie restriction and cardiometabolic risk (CALERIE): exploratory outcomes of a multicentre, phase 2, randomised controlled trial

W Kraus, M Bhapkar, K Huffman, C Pieper, S Krupa Das, L Redman et al.. The Lancet Diabetes & Endocrinology. 2019.

Published 2026-10-15Sources checked 2026-10-151 sourceEverstack research teamHow we work

In plain language

CALERIE: about 12% calorie restriction for 2 years improved many cardiometabolic risk factors in healthy non-obese adults.

Limits

Risk factors, not disease outcomes.

Source

doi.org/10.1016/S2213-8587(19)30151-2 · PubMed 31303390 · Free full text

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