BMeta-analysis of RCTs · 26 RCTs, 2,160

Efficacy of omega-3 PUFAs in depression: A meta-analysis

Y Liao, B Xie, H Zhang, Q He, L Guo, M Subramanieapillai et al.. Translational Psychiatry. 2019.

Published 2026-10-15Sources checked 2026-10-151 sourceEverstack research teamHow we work

In plain language: EPA-dominant (≥60%) omega-3 at up to 1 g EPA improved depressive symptoms; DHA-dominant did not.
Limits: Heterogeneity; small trials.
Source: doi.org/10.1038/s41398-019-0515-5 · PubMed 31383846 · Free full text

Summary written by Everstack from the published abstract. Verified against Crossref on 2026-10-15. The authors do not endorse Everstack.