DLast reviewed
Spermidine
Mouse lifespan data plus human dietary associations.
Editorial section. Research summaries are not product claims and contain no product links or offers. A summary is never proof that any product works.
- The question
- What is the evidence for spermidine and longevity?
- Study design
- Mouse feeding studies and an analysis of dietary spermidine and blood pressure and heart outcomes in a human cohort (2016). [1]
- What they found
- Spermidine extended lifespan and supported heart function in mice. In people, higher dietary intake was associated with lower blood pressure and fewer cardiovascular events. [1]
- Limitations
- Human data are observational; diet quality may explain the link.
- What this does not mean
- Foods like wheat germ, soy and aged cheese contain spermidine. Supplements are unproven.
- Sources
- Eisenberg T et al. Nat Med. 2016;22:1428-1438. doi.org/10.1038/nm.4222
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