Everstack Evidence

ALast reviewed

Creatine: strength, muscle and the aging body

Many randomized trials and meta-analyses, consistent direction of effect, long safety record in healthy adults.

Published Sources checked 3 sourcesEverstack research teamHow we work

Human skeletal muscle, electron micrograph: paired mitochondria sit beside each Z-line
Human skeletal muscle, electron micrograph: paired mitochondria sit beside each Z-line. Image: Louisa Howard, Dartmouth Electron Microscope Facility, Public domain

Editorial section. Research summaries are not product claims and contain no product links or offers. A summary is never proof that any product works.

The question
Does creatine plus resistance training improve strength and lean mass, including in older adults?
Study design
ISSN position stand (2017) and a meta-analysis of 22 randomized trials in older adults (2017). [1][2][3]
What they found
Adding creatine to resistance training produced greater gains in lean tissue and upper and lower body strength than training alone. Typical maintenance intake is 3 to 5 g per day. A separate systematic review found possible short-term memory benefits, with weaker evidence. [1][2][3]
Limitations
Effects depend on training. Most trials last weeks to months, not years. Cognitive findings come from small, varied studies.
What this does not mean
Creatine does not replace training, and it is not a treatment for any condition.
Sources
  1. Kreider RB et al. J Int Soc Sports Nutr. 2017;14:18. doi.org/10.1186/s12970-017-0173-z
  2. Chilibeck PD et al. Open Access J Sports Med. 2017;8:213-226. doi.org/10.2147/OAJSM.S123529
  3. Avgerinos KI et al. Exp Gerontol. 2018;108:166-173. doi.org/10.1016/j.exger.2018.04.013

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